English Papers

Department of Ophthalmology, Hokkaido University
Department of Ophthalmology, Sapporo Medical University
Department of Cardiac Surgery, Asahikawa Medical University
Department of Anesthesiology and Critical care, Asahikawa Medical University
Department of Ophthalmology, Tohoku University
Department of Obstetrics and Gynecology, Tohoku University
Department of Ophthalmology, Akita University
Department of Ophthalmology, Gunma University
Department of Ophthalmology, Niigata University
Department of Ophthalmology, University of Toyama
Department of Ophthalmology, Toho University Sakura Medical Center
Department of Ophthalmology, Toho University Omori Medical Center
Department of Ophthalmology, Toho University Ohashi Medical Center
Department of Neurosurgery, Toho University Ohashi Medical Center
Department of Ophthalmology, University of Tokyo
Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University
Department of Ophthalmology, Tokyo Medical and Dental University
Tokyo Institute of Technology
Faculty of Sport Sciences, Waseda University
Faculty of Commerce, Yokohama College of Commerce
Ophthalmology and Visual Science, Kanazawa University
Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University
Department of Ophthalmology, Nagoya University
Department of Ophthalmology, Osaka Medical College
Nakano Eye Clinic
Tane Memorial Eye Hospital
Department of Ophthalmology, Kyoto University
Department of Ophthalmology, Saneikai Tsukazaki Hospital
Department of Ophthalmology, Nara Medical University
Department of Anesthesiology, Nara Medical University
Department of Ophthalmology, Tokushima University
Department of Ophthalmology, Kyushu University
Institute of Health Science, Kyushu University
Department of Ophthalmology, University of Occupational and Environmental Health
Yamana Eye Hospital
Department of Ophthalmology, Saga University
Department of Ophthalmology, Nagasaki University
Department of Ophthalmology, University of Miyazaki
Devers Eye Institute, Legacy Health System
Department of Veterinary Medicine & Surgery, University of Missouri
Department of Clinical Pharmacology, Medical University of Vienna
Department for Ophthalmology, Kepler University Hospital
Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital
Universiti Teknologi PETRONAS
Senju Pharmaceutical Co.,Ltd
Department of Computer Science and Electronics, Kyushu Institute of Technology


Department of Ophthalmology, Hokkaido University

  1. Hirose S, Saito W, Yoshida K, Saito M, Dong Z, Namba K, Satoh H, Ohno S.
    Elevated choroidal blood flow velocity during systemic corticosteroidtherapy in Vogt-Koyanagi-Harada disease
    Acta Ophthalmol. 2008 Dec;86(8):902-7. Epub 2008 Nov 12.
  2. Michiyuki Saito, Kazuhiko Yoshida, Wataru Saito, Akio Fujiya, Kazuhiro Ohgami, Nobuyoshi Kitaichi, Hiroki Tsukahara, Susumu Ishida and Shigeaki Ohno
    Astaxanthin increases choroidal blood flow velocity
    Graefe's Archive for Clinical and Experimental Ophthalmology ,Vol.250, No.2, 239-245, DOI: 10.1007/s00417-011-1843-1, 2012.
  3. Hashimoto Y, Saito W, Mori S, Saito M, Ishida S
    Increased macular choroidal blood flow velocity during systemic corticosteroid therapy in a patient with acute macular neuroretinopathy
    Clinical Ophthalmology, 2012:6, 1645-1649
  4. Michiyuki Saito, Wataru Saito, Yuki Hashimoto, Chikako Yoshizawa, Akio Fujiya, Kousuke Noda, Susumu Ishida
    Macular choroidal blood flow velocity decreases with regression of acute central serous chorioretinopathy
    Br J Ophthalmol doi:10.1136/bjophthalmol-2012-302349
  5. Michiyuki Saito, Wataru Saito, Yuki Hashimoto, Chikako Yoshizawa, Yasuhiro Shinmei, Kousuke Noda, Susumu Ishida
    Correlation between decreased choroidal blood flow velocity and the pathogenesis of acute zonal occult outer retinopathy
    Clinical and Experimental Ophthalmology, DOI:10.1111/ceo.12143
  6. Ai Takahashi, Wataru Saito, Yuki Hashimoto, Michiyuki Saito, Susumu Ishida
    Impaired Circulation in the Thickened Choroid of a Patient with Serpiginous Choroiditis
    Ocular Immunology and Inflammation, Posted online on April 11, 2014. doi:10.3109/09273948.2014.902075
  7. Kiriko Hirooka, Wataru Saito, Kousuke Noda and Susumu Ishida
    Enhanced-depth Imaging Optical Coherence Tomography and Laser Speckle Flowgraphy in a Patient with Acute Macular Neuroretinopathy
    Ocular Immunology & Inflammation, (0), 1-5, 2014. doi:10.3109/09273948.2014.916305
  8. Kiriko Hirooka, Wataru Saito, Yuki Hashimoto, Michiyuki Saito and Susumu Ishida
    Increased macular choroidal blood flow velocity and decreased choroidal thickness with regression of punctate inner choroidopathy
    BMC Ophthalmology, 14(1), 73, 2014.
  9. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Kiriko Hirooka, Shohei Mori, Kousuke Noda and Susumu Ishida
    Decreased choroidal blood flow velocity in the pathogenesis of multiple evanescent white dot syndrome
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2014, 1-8.
  10. Kiriko Hirooka, Wataru Saito, Kenichi Namba, Yuko Takemoto, Kazuomi Mizuuchi, Tomoe Uno, Yoshiaki Tagawa, Yuki Hashimoto and Susumu Ishida
    Relationship between choroidal blood flow velocity and choroidal thickness during systemic corticosteroid therapy for Vogt–Koyanagi–Harada disease
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2015, 1-9.
  11. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Kiriko Hirooka, Shohei Mori, Kousuke Noda and Susumu Ishida
    Increased choroidal blood flow velocity with regression of unilateral acute idiopathic maculopathy
    Japanese Journal of Ophthalmology, 2015, 1-9.
  12. Michiyuki Saito, Wataru Saito, Kiriko Hirooka, Yuki Hashimoto, Shohei Mori, Kousuke Noda and Susumu Ishida
    Pulse Waveform Changes in Macular Choroidal Hemodynamics With Regression of Acute Central Serous Chorioretinopathy
    Investigative Ophthalmology & Visual Science, 56(11), 6515-6522, 2015.
  13. Kiriko Hirooka, Wataru Saito , Michiyuki Saito, Yuki Hashimoto, Shohei Mori, Kousuke Noda and Susumu Ishida
    Increased choroidal blood flow velocity with regression of acute posterior multifocal placoid pigment epitheliopathy
    Japanese Journal of Ophthalmology, 2016, 1-7.
  14. Yuko Takemoto, Kenichi Namba, Kazuomi Mizuuchi, Daiju Iwata, Tomoe Uno, Shigeaki Ohno, Kiriko Hirooka, Yuki Hashimoto, Wataru Saito, Kazuhisa Sugiyama and Susumu Ishida
    Choroidal circulation impairment during the anterior recurrence of Vogt–Koyanagi–Harada disease confirmed with indocyanine green angiography and laser speckle flowgraphy
    Acta Ophthalmologica, 2016.
  15. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Yuka Hasegawa, Akari Takita, Shohei Mori, Kousuke Noda and Susumu Ishida
    Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy
    Journal of Ophthalmology, 2017.
  16. Michiyuki Saito, Kousuke Noda, Wataru Saito and Susumu Ishida
    Relationship between choroidal blood flow velocity and choroidal thickness in patients with regression of acute central serous chorioretinopathy
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s0041, 2017.
  17. Akari Takita, Yuki Hashimoto, Wataru Saito, Satoru Kase and Susumu Ishida
    Changes in blood flow velocity and thickness of the choroid in a patient with leukemic retinopathy
    American journal of ophthalmology case reports, doi:10.1016/j.ajoc.2018.09.001, 2018.
  18. Iku Kikuchi, Satoru Kase, Yuki Hashimoto, Kiriko Hirooka and Susumu Ishida
    Involvement of circulatory disturbance in optic disk melanocytoma with visual dysfunction
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-019-04257-7, 2019.

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Department of Ophthalmology, Sapporo Medical University

  1. H.Tagawa, H. Furukawa and H. Fujii
    Effect of topical timolol on the blood velocity of the iris microcirculation and the aqueous veins
    Invest Ophthalmol Vis. Sci. 1993, 34(Suppl): 927
  2. H.Tagawa, H. Furukawa and H. Fujii
    Dynamic Ocular Blood Flow Image Using Laser Speckle Flowgraphy
    Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
  3. Hiroshi Tagawa, Hideki Furukawa and Hitoshi Fujii
    Changes of Blood Circulation in Human Eyes with Retinal Diseases Using Real-Time Laser Flowgraphy
    Proc. 3rd Internet World Congress on Biomedical Sciences, 1996
  4. Tagawa H, Kawaguchi S,Furukawa H, and Fujii H.
    Effect of retrobulbar injection of unoprostone on the rabbit ocular microcirculation
    Invest Ophthalmol Vis Sci 1997, 38(Suppl): 782
  5. Kawaguchi S, Tagawa H, Maeda T, Suzuki J, and Fujii H.
    Circulatory changes of retinal vessels and choroidal microcirculation in eyes with arterial occlusive disease
    Invest Ophthalmol Vis Sci 1997, 38(Suppl): 1047
  6. Tagawa H, Nakagawa H,Furukawa H, and Fujii H.
    Visualization and quantitative evaluation of pulsatile ocular microcirculation by laser speckle flowgraphy
    Invest Ophthalmol Vis Sci 1998, 39(Suppl): 267
  7. Sasaki N, Tagawa H, Katsuta S, Nakagawa T andFujii H.
    Long term effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in normals
    Invest Ophthalmol Vis Sci 1998, 39(Suppl): 271
  8. Tashimo A,Tagawa H, Kawaguchi S, Suzuki T, Nakagawa T and Fujii H.
    Effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in eyes with arterial occlusive disease
    Invest Ophthalmol Vis Sci 1998, 39(Suppl): 999
  9. Katsuta S, Tagawa H, Suzuki T, Sasaki N, Nakagawa T and Fujii H.
    Short term effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in normals
    Invest Ophthalmol Vis Sci 1998, 39(Suppl): 1000
  10. Tagawa H,Sasaki N,Tashimo A, Suzuki T, Shimizu M, Fujii H.
    Estimation of real blood velocity measured by laser speckle flowgraphy at retinal vessels
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 369
  11. Sasaki N, Tagawa H, Shimizu M, Suzuki T, Fujii H.
    Changes of pulsatility at retinal arteries as aging
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 488
  12. Katsuta S,Shimizu M, Tagawa H, Sasaki N, Suzuki T, Fujii H.
    Changes of pulsatility at choroidal microcirculation as aging
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 488
  13. Tashimo A, Tagawa H, Sasaki N, Suzuki T, Fujii H.
    Changes of pulsatility at retinal arteries and choroidal microcirculation in patients with arteriosclerosis
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 681
  14. Kimihito Maeda, Futoshi Ishikawa, Hiroshi Ohguro
    Ocular blood flow levels and visual prognosis in a patient with nonischemic type central retinal vein occlusion
    Clinical Ophthalmology 2009:3 489-491
  15. Hiroshi Ohguro, Ikuyo Ohguro, Maki Katai, Sachie Tanaka
    Two-Year Randomized, Placebo-Controlled Study of Black Currant Anthocyanins on Visual Field in Glaucoma
    Ophthalmologica(DOI: 10.1159/000335961), 2012.
  16. Ikuyo Ohguro, Hiroshi Ohguro
    The Effects of a Fixed Combination of 0.5% Timolol and 1% Dorzolamide on Optic Nerve Head Blood Circulation
    Journal of Ocular Pharmacology and Therapeutics (doi:10.1089/jop.2011.0243.), 2012.

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Department of Cardiac Surgery, Asahikawa Medical University

  1. Fumiaki Kimura, Hirotsugu Kanda, Yuki Toyama, Takayuki Kunisawa, Taiji Nagaoka, Akitoshi Yoshida, Hiroto Kitahara and Hiroyuki Kamiya
    Evaluation of cerebral circulation during retrograde perfusion by laser speckle flowgraphy
    General Thoracic and Cardiovascular Surgery, doi:10.1007/s11748-016-0727-z, 2016.
  2. Hiroto Kitahara, Hirotsugu Kanda, Fumiaki Kimura, Tomohiro Takeda, Shingo Kunioka, Takayuki Kunisawa and Hiroyuki Kamiya
    Cerebral circulation estimated by laser speckle flowgraphy in retrograde femoral arterial perfusion during minimally invasive cardiac surgery.
    Interactive cardiovascular and thoracic surgery, 25(1), 25-29, doi:10.1093/icvts/ivx046, 2017.

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Department of Anesthesiology and Critical care, Asahikawa Medical University

  1. Hirotsugu Kanda, Fumiaki Kimura, Takafumi Iida, Megumi Kanao-Kanda, Takayuki Kunisawa, Taiji Nagaoka, Akitoshi Yoshida and Hiroyuki Kamiya
    Combined Use of Intra-aortic Balloon Pump and Venoarterial Extracorporeal Membrane Oxygenation Support With Femoral Arterial Cannulation Impairs Cerebral Microcirculation: Evaluation With Laser Speckle Flowgraphy
    Journal of Cardiothoracic and Vascular Anesthesia, doi:10.1053/j.jvca.2016.09.012, 2016.
  2. Hirotsugu Kanda, Hiroto Kitahara, Yuki Toyama, Megumi Kanao-Kanda, Takayuki Kunisawa and Hiroyuki Kamiya
    Intra-aortic Balloon Pump Does Not Impede Cerebral Microcirculation During Central Extracorporeal Membrane Oxygenation Support: Evaluation With Laser Speckle Flowgraphy
    Journal of Cardiothoracic and Vascular Anesthesia, 31(4), e67-e68, doi:10.1053/j.jvca.2017.04.030, 2017.
  3. Hirotsugu Kanda, TakayukiKunisawa, Hiroto Kitahara, Takafumi Iida, Yuki Toyama, Megumi Kanao-Kanda, Chie Mori and Hiroyuki Kamiya
    Cerebral Hypoxia Caused by Flow Confliction During Minimally Invasive Cardiac Surgery With Retrograde Perfusion: A Word of Caution
    Journal of Cardiothoracic and Vascular Anesthesia, 32(4), 1838-1840, doi:10.1053/j.jvca.2017.10.007, 2017.
  4. Hirotsugu Kanda, Takayuki Kunisawa, Takafumi Iida, Masahiro Tada, Fumiaki Kimura, Hayato Ise and Hiroyuki Kamiya
    Cerebral circulation during retrograde cerebral perfusion: evaluation using laser speckle flowgraphy
    The Annals of Thoracic Surgery, doi:10.1016/j.athoracsur.2018.11.067, 2018.

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Department of Ophthalmology, Tohoku University

  1. Naoko Aizawa, Yu Yokoyama, Naoki Chiba, Kazuko Omodaka, Masayuki Yasuda, Takaaki Otomo, Masahiko Nakamura, Nobuo Fuse, Toru Nakazawa
    Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma
    Clinical Ophthalmology, 2011:5, 1171-1176
  2. Naoki Chiba, Kazuko Omodaka, Yu Yokoyama, Naoko Aizawa, Satoru Tsuda, Masayuki Yasuda, Takaaki Otomo, Shunji Yokokura, Nobuo Fuse, Toru Nakazawa
    Association between optic nerve blood flow and objective examinations in glaucoma patients with generalized enlargement disc type
    Clinical Ophthalmology, 2011:5, 1549-1556
  3. Yu Yokoyama, Naoko Aizawa, Naoki Chiba, Kazuko Omodaka, Masahiko Nakamura, Takaaki Otomo, Shunji Yokokura, Nobuo Fuse, Toru Nakazawa
    Significant correlations between optic nerve head microcirculation and visual field defects and nerve fiber layer loss in glaucoma patients with myopic glaucomatous disk
    Clinical Ophthalmology, 2011:5, 1721 - 1727
  4. Tsuda, Satoru MD; Yokoyama, Yu MD; Chiba, Naoki MD; Aizawa, Naoko MD; Shiga, Yukihiro MD; Yasuda, Masayuki MD; Yokokura, Shunji PhD, MD; Otomo, Takaaki MD; Fuse, Nobuo PhD, MD; Nakazawa, Toru PhD, MD
    Effect of Topical Tafluprost on Optic Nerve Head Blood Flow in Patients With Myopic Disc Type
    Journal of Glaucoma, POST AUTHOR CORRECTIONS, 2 April 2013, doi: 10.1097/IJG.0b013e318237c8b3
  5. Naoko Aizawa MD, Hiroshi Kunikata MD PhD, Yu Yokoyama MD, Toru Nakazawa MD PhD
    Correlation between optic disc microcirculation in glaucoma measured with laser speckle flowgraphy and fluorescein angiography, and the correlation with mean deviation
    Clinical & Experimental Ophthalmology, DOI: 10.1111/ceo.12130
  6. Yukihiro Shiga, Masahiko Shimura, Toshifumi Asano, Satoru Tsuda, Yu Yokoyama, Naoko Aizawa,
    Kazuko Omodaka, Morin Ryu, Shunji Yokokura, Takayuki Takeshita and Toru Nakazawa
    The Influence of Posture Change on Ocular Blood Flow in Normal Subjects, Measured by Laser Speckle Flowgraphy
    Current Eye Research, June 2013, Vol. 38, No. 6 , Pages 691-698 (doi:10.3109/02713683.2012.758292)
  7. Yukihiro Shiga, Kazuko Omodaka, Hiroshi Kunikata, Morin Ryu, Yu Yokoyama, Satoru Tsuda, Toshifumi Asano, Shigeto Maekawa, Kazuichi Maruyama, Toru Nakazawa
    Waveform analysis of ocular blood flow and the early detection of normal-tension glaucoma
    IOVS, October 15, 2013 IOVS-13-12930(doi:10.1167/iovs.13-12930)
  8. Shin Takayama, Yukihiro Shiga, Taiki Kokubun, Hideyuki Konno, Noriko Himori, Morin Ryu, Takehiro Numata, Soichiro Kaneko, Hitoshi Kuroda, Junichi Tanaka, Seiki Kanemura, Tadashi Ishii, Nobuo Yaegashi, Toru Nakazawa
    The traditional kampo medicine tokishakuyakusan increases ocular blood flow in healthy subjects
    Evidence-Based Complementary and Alternative Medicine, 2014.
  9. Satoru Tsuda, Hiroshi Kunikata, Masahiko Shimura, Naoko Aizawa, Kazuko Omodaka, Yukihiro Shiga, Masayuki Yasuda, Yu Yokoyama, Toru Nakazawa
    Pulse-Waveform Analysis of Normal Population using Laser Speckle Flowgraphy
    Current Eye Research, Posted online on April 21, 2014. (doi:10.3109/02713683.2014.905608)
  10. Yukihiro Shiga, Toshifumi Asano, Hiroshi Kunikata, Fumihiko Nitta, Hajime Sato, Toru Nakazawa and Masahiko Shimura
    Relative flow volume, a novel blood flow index in the human retina derived from laser speckle flowgraphy
    Investigative Ophthalmology & Visual Science, IOVS-14, 2014. (doi: 10.1167/iovs.14-14116)
  11. Fumihiko Nitta, Hiroshi Kunikata, Naoko Aizawa, Kazuko Omodaka, Yukihiro Shiga, Masayuki Yasuda and Toru Nakazawa
    The effect of intravitreal bevacizumab on ocular blood flow in diabetic retinopathy and branch retinal vein occlusion as measured by laser speckle flowgraphy
    Clinical Ophthalmology, 2014:8, 1119 - 1127
  12. Naoko Aizawa, Hiroshi Kunikata, Yu Yokoyama and Toru Nakazawa
    Correlation between optic disc microcirculation in glaucoma measured with laser speckle flowgraphy and fluorescein angiography, and the correlation with mean deviation
    Clinical & experimental ophthalmology, 42(3), 293-294.
  13. Shunsuke Omodaka, Hidenori Endo, Hiroshi Doi, Hiroaki Shimizu, Miki Fujimura, Naoko Aizawa, Toru Nakazawa and Teiji Tominaga
    Usefulness of Laser Speckle Flowgraphy for the Assessment of Ocular Blood Flow in Extracranial Intracranial Bypass
    Journal of Stroke and Cerebrovascular Diseases (2014).
  14. Naoko Aizawa, Hiroshi Kunikata, Yukihiro Shiga, Yu Yokoyama, Kazuko Omodaka and Toru Nakazawa
    Correlation between structure/function and optic disc microcirculation in myopic glaucoma, measured with laser speckle flowgraphy.
    BMC Ophthalmology, 14(1), 113.
  15. Naoko Aizawa, Fumihiko Nitta, Hiroshi Kunikata, Tetsuya Sugiyama, Tsunehiko Ikeda, Makoto Araie and Toru Nakazawa
    Laser speckle and hydrogen gas clearance measurements of optic nerve circulation in albino and pigmented rabbits with or without optic disc atrophy.
    Investigative Ophthalmology & Visual Science, IOVS-14, 2014. doi: 10.1167/iovs.14-15373
  16. Wataru Kobayashi, Hiroshi Kunikata, Kazuko Omodaka, Kyousuke Togashi, Morin Ryu, Masahiro Akiba, Gaku Takeuchi, Tetsuya Yuasa, and Toru Nakazawa
    Correlation of Optic Nerve Microcirculation with Papillomacular Bundle Structure in Treatment Naive Normal Tension Glaucoma
    Journal of Ophthalmology, vol. 2014, Article ID 468908, 9 pages, 2014. doi:10.1155/2014/468908
  17. Hiroshi Kunikata, Naoko Aizawa, Masataka Kudo, Shunji Mugikura, Fumihiko Nitta, Ryo Morimoto, Yoshitsugu Iwakura, Yoshikiyo Ono, Fumitoshi Satoh, Hidetoshi Takahashi, Sadayoshi Ito, Shoki Takahashi and Toru Nakazawa
    Relationship of Ocular Microcirculation, Measured by Laser Speckle Flowgraphy, and Silent Brain Infarction in Primary Aldosteronism
    PLOS ONE, 10(2), e0117452, 2015.
  18. Noriko Himori, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka, Kazuichi Maruyama, Hidetoshi Takahashi and Toru Nakazawa
    The association between systemic oxidative stress and ocular blood flow in patients with normal-tension glaucoma
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1-9, 2015.
  19. Hiroshi Kunikata, Toru Nakazawa
    Recent Clinical Applications of Laser Speckle Flowgraphy in Eyes with Retinal Disease.
    The Asia-Pacific Journal of Ophthalmology, 2015
  20. Naoko Aizawa, Hiroshi Kunikata, Fumihiko Nitta, Yukihiro Shiga, Kazuko Omodaka, Satoru Tsuda and Toru Nakazawa
    Age-and Sex-Dependency of Laser Speckle Flowgraphy Measurements of Optic Nerve Vessel Microcirculation.
    PLOS ONE, 11(2), e0148812, 2016.
  21. Toru Nakazawa
    Ocular Blood Flow and Influencing Factors for Glaucoma.
    The Asia-Pacific Journal of Ophthalmology, 5(1), 38-44, 2016.
  22. Maki Inoue, Noriko Himori, Hiroshi Kunikata, Takayuki Takeshita, Naoko Aizawa, Yukihiro Shiga,Kazuko Omodaka, Koji M Nishiguchi, Hidetoshi Takahashi and Toru Nakazawa
    The reduction of temporal optic nerve head microcirculation in autosomal dominant optic atrophy
    Acta ophthalmologica, 94(7), e580-e585, doi:10.1111/aos.12999, 2016.
  23. Kazuko Omodaka, Seri Takahashi, Akiko Matsumoto, Shigeto Maekawa, Tsutomu Kikawa, Noriko Himori, Hidetoshi Takahashi, Kazuichi Maruyama, Hiroshi Kunikata, Masahiro Akiba and Toru Nakazawa
    Clinical Factors Associated with Lamina Cribrosa Thickness in Patients with Glaucoma, as Measured with Swept Source Optical Coherence Tomography
    PLOS ONE, 11(4), e0153707, 2016.
  24. Kazuki Hashimoto, Hiroshi Kunikata, Masayuki Yasuda, Azusa Ito, Naoko Aizawa, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Yoshimasa Takano, Koji M. Nishiguchi, Hideki Katagiri and Toru Nakazawa
    The relationship between advanced glycation end products and ocular circulation in type 2 diabetes
    Journal of Diabetes and its Complications, 2016.
  25. Yukihiro Shiga, Hiroshi Kunikata, Naoko Aizawa, Naoki Kiyota, Yukiko Maiya, Yu Yokoyama, Kazuko Omodaka, Hidetoshi Takahashi, Tomoki Yasui, Keiichi Kato, Aiko Iwase and Toru Nakazawa
    Optic Nerve Head Blood Flow, as Measured by Laser Speckle Flowgraphy, Is Significantly Reduced in Preperimetric Glaucoma
    Current Eye Research, doi:10.3109/02713683.2015.1127974, 2016.
  26. Naoki Kiyota, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Relationship between laser speckle flowgraphy and optical coherence tomography angiography measurements of ocular microcirculation
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-017-3627-8, 1-10, 2017.
  27. Naoki Kiyota, Yukihiro Shiga, Shiori Suzuki, Marika Sato, Naoko Takada, Shigeto Maekawa, Kazuko Omodaka, Kazuichi Maruyama, Hiroshi Kunikata and Toru Nakazawa
    The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients
    Investigative Ophthalmology and Visual Science, 58(7), 3181-3188, doi: 10.1167/iovs.17-21648, 2017.
  28. Kazuichi Maruyama, Aya Noguchi, Ai Shimizu, Yukihiro Shiga, Hiroshi Kunikata and Toru Nakazawa
    Predictors of Recurrence in Vogt-Koyanagi-Harada Disease
    Ophthalmology Retina, doi: 10.1016/j.oret.2017.07.016, 2017.
  29. Naoki Kiyota, Hiroshi Kunikata, Seri Takahashi, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Factors associated with deep circulation in the peripapillary chorioretinal atrophy zone in normal-tension glaucoma with myopic disc
    Acta Ophthalmologica, doi:10.1111/aos.13621, 2017.
  30. Naoko Aizawa, Hiroshi Kunikata, Yukihiro Shiga, Satoru Tsuda, Yu Yokoyama, Kazuko Omodaka, Tomoki Yasui, Keiichi Kato, Hiroaki Kurashima, Etsuyo Miyamoto, Masayo Hashimoto and Toru Nakazawa
    Preperimetric Glaucoma Prospective Observational Study (PPGPS): Design, baseline characteristics, and therapeutic effect of tafluprost in preperimetric glaucoma eye
    PLOS ONE, 12(12), e0188692, doi:10.1371/journal.pone.0188692, 2017.
  31. Yukihiro Shiga, Koji M. Nishiguchi, Yosuke Kawai, Kaname Kojima, Kota Sato, Kosuke Fujita, Mai Takahashi, Kazuko Omodaka, Makoto Araie, Kenji Kashiwagi, Makoto Aihara, Takeshi Iwata, Fumihiko Mabuchi, Mitsuko Takamoto, Mineo Ozaki, Kazuhide Kawase, Nobuo Fuse, Masayuki Yamamoto, Jun Yasuda, Masao Nagasaki, Toru Nakazawa , for the Japan Glaucoma Society Omics Group (JGS-OG)
    Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.
    PloS one, 12(12), e0186678, doi:10.1371/journal.pone.0186678, 2017.
  32. Kazuko Omodaka, Guangzhou An, Satoru Tsuda, Yukihiro Shiga, Naoko Takada, Tsutomu Kikawa, Hidetoshi Takahashi, Hideo Yokota, Masahiro Akiba and Toru Nakazawa
    Classification of optic disc shape in glaucoma using machine learning based on quantified ocular parameters
    PloS one, 12(12), e0190012, doi:10.1371/journal.pone.0190012, 2017.
  33. Yukihiro Shiga, Naoko Aizawa, Satoru Tsuda, Yu Yokoyama, Kazuko Omodaka, Hiroshi Kunikata, Tomoki Yasui, Keiichi Kato, Hiroaki Kurashima, Etsuyo Miyamoto, Masayo Hashimoto and Toru Nakazawa
    Preperimetric Glaucoma Prospective Study (PPGPS): Predicting Visual Field Progression With Basal Optic Nerve Head Blood Flow in Normotensive PPG Eyes
    Translational vision science and technology, 7(1), 11, doi:10.1167/tvst.7.1.11, 2018.
  34. Naoki Kiyota, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Ocular microcirculation measurement with laser speckle flowgraphy and optical coherence tomography angiography in glaucoma.
    Acta Ophthalmologica, doi:10.1111/aos.13639, 2018.
  35. Naoki Kiyota, Yukihiro Shiga, Kohei Ichinohasama, Masayuki Yasuda, Naoko Aizawa, Kazuko Omodaka, Naoto Honda, Hiroshi Kunikata and Toru Nakazawa
    The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow
    Investigative Ophthalmology & Visual Science, 59(8), 3488-3496, 2018.
  36. Maki Inoue-Yanagimachi, Noriko Himori, Kota Sato, Taiki Kokubun, Toshifumi Asano, Yukihiro Shiga, Satoru Tsuda, Hiroshi Kunikata and Toru Nakazawa
    Association between mitochondrial DNA damage and ocular blood flow in patients with glaucoma
    British Journal of Ophthalmology, doi:10.1136/bjophthalmol-2018-312356, 2018.
  37. Kohei Ichinohasama, Hiroshi Kunikata, Azusa Ito, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Hideki Katagiri and Toru Nakazawa
    The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes
    Journal of Ophthalmology, doi:10.1155/2019/3421305, 2019.

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Department of Obstetrics and Gynecology, Tohoku University

  1. Takahiro Sato, Junichi Sugawara , Naoko Aizawa, Noriyuki Iwama, Fumiaki Takahashi, Michiyo Nakamura-Kurakata, Masatoshi Saito, Takashi Sugiyama, Hiroshi Kunikata, Toru Nakazawa and Nobuo Yaegashi
    Longitudinal changes of ocular blood flow using laser speckle flowgraphy during normal pregnancy
    PLOS ONE, 12(3), e0173127, doi:10.1371/journal.pone.0173127, 2017.

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Department of Ophthalmology, Akita University

  1. Yusuke Ohta, Sanae Takaseki and Takeshi Yoshitomi
    Effects of ripasudil hydrochloride hydrate (K-115), a Rho-kinase inhibitor, on ocular blood flow and ciliary artery smooth muscle contraction in rabbits
    Japanese journal of ophthalmology, 61(5), 423–432, 2017.
  2. Ya-Ru Dong, Shi-Wei Huang, Ji-Zhe Cui and Takeshi Yoshitomi
    Effects of brinzolamide on rabbit ocular blood flow in vivo and ex vivo
    International Journal of Ophthalmology, 11(5), 719–725, 2018.

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Department of Ophthalmology, Gunma University

  1. Hiroaki Isono, Shoji Kishi, Yasutaka Kimura, Naoya Hagiwara, Naoki Konishi and Hitoshi Fujii
    Observation of Choroidal Circulation Using Index of Erythrocytic Velocity
    Arch Ophthalmol, 121, no.2, 225-231, 2003.
  2. A. Otsubo, S. Kishi, K. Ohkoshi and T. Ymaguchi
    The Influence of Peripheral Retinal Detachment in Choroidal Blood Flow of the Macula
    ARVO, 2003, (3004/B843)
  3. Watanabe G, Fujii H, Kishi S
    Imaging of Choroidal Hemodynamics in Eyes with Polypoidal Choroidal Vasculopathy Using Laser Speckle Phenomenon
    Jpn J Ophthalmol 52: 204-210, 2008
  4. Yoichiro Shinohara, Tomoyuki Kashima, Hideo Akiyama, Shoji Kishi
    Alteration of choroidal thickness in a case of carotid cavernous fistula: a case report and a review of the literature
    BMC Ophthalmology 2013, 13:75 doi:10.1186/1471-2415-13-75
  5. Yoichiro Shinohara, Tomoyuki Kashima, Hideo Akiyama, Yukitoshi Shimoda, Danjie Li and Shoji Kishi
    Evaluation of Fundus Blood Flow in Normal Individuals and Patients with Internal Carotid Artery Obstruction Using Laser Speckle Flowgraphy
    PLOS ONE, 12(1), e0169596, 2017.

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Department of Ophthalmology, Niigata University

  1. Kiyoshi Yaoeda, Motohiro Shirakashi, Shigeo Funaki, Haruko Funaki, Tomoko Nakatsue, Atsushi Fukushima
    Measurement of Microcirculation in the Optic Nerve Head by Laser Speckle Flowgraphy and Scanning Laser Doppler Flowmetry.
    Am. J. Ophthalmol., 129, NO. 6, 734-739, 2000.
  2. Kiyoshi Yaoeda, Motohiro Shirakashi, Shigeo Funaki, Haruko Funaki, Tomoko Nakatsue, Atsushi Fukushima AND Haruki Abe
    Measurement of Microcirculation in Optic Nerve Head by Laser Speckle Flowgraphy in Normal Volunteers
    Am. J. Ophthalmol., 130, NO. 5, 606-610, 2000.
  3. Kiyoshi Yaoeda, Motohiro Shirakashi, Atsushi Fukushima, Shigeo Funaki, Haruko Funaki, Haruki Abe and Naohito Tanabe
    Relationship between optic nerve head microcirculation and visual field loss in glaucoma.
    Acta Ophthalmol. Scand, 81, 253-259, 2003.

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Department of Ophthalmology, University of Toyama

  1. Yuta Takata, Yasuhito Nitta, Akio Miyakoshi and Atsushi Hayashi
    Retinal Endovascular Surgery with Tissue Plasminogen Activator Injection for Central Retinal Artery Occlusion
    Case Reports in Ophthalmology, 9(2), 327-332, doi:10.1159/000489696, 2018.

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Department of Ophthalmology, Toho University Sakura Medical Center

  1. Tomoaki Shiba, Mao Takahashi, Yuichi Hori and Takatoshi Maeno
    Pulse-wave analysis of optic nerve head circulation is significantly correlated with brachialankle pulse-wave velocity, carotid intima media thickness, and age
    Graefe's Archive for Clinical and Experimental Ophthalmology (DOI: 10.1007/s00417-012-1952-5), 2012.
  2. Shiba T, Takahashi M, Hori Y, Maeno T, Shirai K.
    Optic Nerve Head Circulation Determined by Pulse Wave Analysis is Significantly Correlated with Cardio Ankle Vascular Index, Left Ventricular Diastolic Function, and Age.
    Journal of atherosclerosis and thrombosis, Published online: July 4, 2012.
  3. Tomoaki Shiba, Mao Takahashi, Takatoshi Maeno
    Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated With Kidney Function in Patients With and Without Chronic Kidney Disease
    Journal of Ophthalmology, 2013.
  4. Makoto Ubuka, Tetsuya Sugiyama, Yasutaka Onoda, Tomoaki Shiba, Yuichi Hori, Takatoshi Maeno
    Changes in the Blood Flow of the Optic Nerve Head Induced by Different Concentrations of Epinephrine in Intravitreal Infusion During Vitreous Surgery
    Investigative Ophthalmology & Visual Science, 2014, IOVS-13-13801.
  5. Muramatsu Rina, Tomoaki Shiba, Mao Takahashi, Yuichi Hori and Takatoshi Maeno
    Pulse waveform analysis of optic nerve head circulation for predicting carotid atherosclerotic changes.
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-015-3123-y, 2015.
  6. Ryuya Hashimoto, Asato Hirota and Takatoshi Maeno
    Choroidal blood flow impairment demonstrated using laser speckle flowgraphy in a case of commotio retinae
    American Journal of Ophthalmology Case Reports, doi: 10.1016/j.ajoc.2016.08.002, 2016.
  7. Ryuya Hashimoto, Tetsuya Sugiyama, Makoto Ubuka and Takatoshi Maeno
    Autoregulation of Optic Nerve Head Blood Flow Induced by Elevated Intraocular Pressure during Vitreous Surgery.
    Current Eye Research, doi: 10.1080/02713683.2016.1220592, 2016.
  8. Ryuya Hashimoto, Tetsuya Sugiyama, Hidetaka Masahara, Masashi Sakamoto, Makoto Ubuka and Takatoshi Maeno
    Impaired Autoregulation of Blood Flow at the Optic Nerve Head during Vitrectomy in Patients with Type 2 Diabetes
    American Journal of Ophthalmology, doi: 10.1016/j.ajo.2017.06.021, 2017.
  9. Ryuya Hashimoto, Tetsuya Sugiyama, Makoto Ubuka and Takatoshi Maeno
    Impairment of autoregulation of optic nerve head blood flow during vitreous surgery in patients with hypertension and hyperlipidemia
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-017-3788-5, 2017.
  10. Ryuya Hashimoto, Juri Kawamura, Asato Hirota, Mizuho Oyamada, Asao Sakai and Takatoshi Maeno
    Changes in choroidal blood flow and choroidal thickness after treatment in two cases of pediatric anisohypermetropic amblyopia
    American Journal of Ophthalmology Case Reports, Volume 8, 39-43, doi: 10.1016/j.ajoc.2017.10.010, 2017.
  11. Ryuya Hashimoto, Tetsuya Sugiyama and Takatoshi Maeno
    Comparison of Optic Nerve Head Blood Flow Autoregulation among Quadrants Induced by Decreased Ocular Perfusion Pressure during Vitrectomy
    BioMed Research International, vol. 2017, Article ID 6041590, 6 pages, doi:10.1155/2017/6041590, 2017.
  12. Ryuya Hashimoto, Mizuho Oyamada and Takatoshi Maeno
    Analysis of Optic Nerve Head Circulation Using Laser Speckle Flowgraphy in a Case of Pediatric Optic Neuritis
    EC Ophthalmology, 9(8), 572-581, 2018.

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Department of Ophthalmology, Toho University Omori Medical Center

  1. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Yuuji Katayama, Tetsushi Arimura, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Reproducibility of Neonate Ocular Circulation Measurements using Laser Speckle Flowgraphy
    BioMed Research International, 2015.
  2. Tomoaki Shiba, Tetsuya Sugiyama, Yuichi Hori, Tadashi Matsumoto, Takatoshi Maeno and Mao Takahashi
    Relationship between plasma levels of vasoactive mediators and optic nerve head circulation shown by laser speckle flowgraphy
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-015-3145-5, 2015.
  3. Tomoaki Shiba , Mao Takahashi, Ryuya Hashimoto, Tadashi Matsumoto and Yuichi Hori
    Pulse waveform analysis in the optic nerve head circulation reflects systemic vascular resistance obtained via a Swan–Ganz catheter.
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3289-y, 2016.
  4. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Yuuji Katayama, Tetsushi Arimura, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3362-6, 2016.
  5. Chieko Shiba, Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Relationship between glycosylated hemoglobin A1c and ocular circulation by laser speckle flowgraphy in patients with/without diabetes mellitus
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3437-4, 2016.
  6. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Kohji Shirai and Yuichi Hori
    Arterial stiffness shown by the cardio-ankle vascular index is an important contributor to optic nerve head microcirculation
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3521-9, 2016.
  7. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Yuichi Hori and Kohji Shirai
    Arterial Stiffness, Monitored with Cardio Ankle Vascular Index is Adjusting The Ocular Microcirculation Obtained from Laser Speckle Flowgraphy.
    Journal of Hypertension, doi: 10.1097/01.hjh.0000501307.42081.00, 2016.
  8. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Kotaro Hine and Yuichi Hori
    A Change in Ocular Circulation after Photocoagulation for Retinopathy of Prematurity in a Neonate
    Case Reports in Ophthalmology, 8(1), 91-98, doi: 10.1159/000456708, 2017.
  9. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Differences in optic nerve head microcirculation between evening and morning in patients with coronary artery disease
    Microcirculation, doi: 10.1111/micc.12386, 2017.
  10. Tadashi Matsumoto, Yuta Saito, Takashi Itokawa, Tomoaki Shiba, Mari S. Oba, Haruo Takahashi and Yuichi Hori
    Retinal VEGF levels correlate with ocular circulation measured by a laser speckle-micro system in an oxygen-induced retinopathy rat model
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-017-3756-0, 2017.
  11. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics
    Journal of Diabetes Research, doi: 10.1155/2017/3141678, 2017.
  12. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Masahiko Tomita, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Decreased ocular blood flow after photocoagulation therapy in neonatal retinopathy of prematurity
    Japanese journal of ophthalmology, doi: 10.1007/s10384-017-0536-7, 2017.
  13. Hironori Osamura, Tomoaki Shiba, Takashi Itokawa, Tadashi Matsumoto and Yuichi Hori
    Relationships among Ocular Blood Flow Shown by Laser Speckle Flowgraphy, Retinal Arteriosclerotic Change, and Chorioretinal Circulation Time Obtained by Fluorescein Angiography
    Journal of Ophthalmology, doi: 10.1155/2017/2969064, 2017.
  14. Tomoaki Shiba, Mao Takahashi, Chieko Shiba, Tadashi Matsumoto and Yuichi Hori
    The relationships between the pulsatile flow form of ocular microcirculation by laser speckle flowgraphy and the left ventricular end-diastolic pressure and mass
    The International Journal of Cardiovascular Imaging, doi: 10.1007/s10554-018-1388-z, 2018.
  15. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Masahiko Tomita, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Intravitreal bevacizumab treatment reduces ocular blood flow in retinopathy of prematurity: a four-case report
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4063-0, 2018.
  16. Tetsushi Arimura, Tomoaki Shiba, Mao Takahashi, Shun Kumashiro, Hironori Osamura. Tadashi Matsumoto, Ken Sakai and Yuichi Hori
    Assessment of ocular microcirculation in patients with end-stage kidney disease
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4137-z, 2018.
  17. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Pulse Waveform Analysis in Ocular Microcirculation by Laser Speckle Flowgraphy in Patients with Left Ventricular Systolic and Diastolic Dysfunction
    Journal of vascular research, 55(6), 329-337, doi:10.1159/000494066, 2018.

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Department of Ophthalmology, Toho University Ohashi Medical Center

  1. Ayako Anraku, Kyoko Ishida, Nobuko Enomoto, Seiji Takagi, Hiroyuki Ito, Asuka Takeyama, Fumihiko Yagi and Goji Tomita
    Association between Optic Nerve Head Microcirculation and Macular Ganglion Cell Complex Thickness in Eyes with Untreated Normal Tension Glaucoma and a Hemifield Defect
    Journal of Ophthalmology, doi: 10.1155/2017/3608396, 2017.
  2. Asuka Takeyama, Kyoko Ishida, Ayako Anraku, Masahiro Ishida and Goji Tomita
    Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma
    Journal of Ophthalmology, doi: 10.1155/2018/1751857, 2018.
  3. Haruka Moroi, Ayako Anraku, Kyoko Ishida and Goji Tomita
    Factors Related to a Right-Left Difference in Visual Field Defect in the Eyes with Untreated Normal Tension Glaucoma
    Journal of Ophthalmology, doi: 10.1155/2018/4595214, 2018.

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Department of Neurosurgery, Toho University Ohashi Medical Center

  1. Masashi Ishii, Morito Hayashi, Fumihiko Yagi, Kenichiro Sato, Goji Tomita and Satoshi Iwabuchi
    Relationship between the Direction of Ophthalmic Artery Blood Flow and Ocular Microcirculation before and after Carotid Artery Stenting.
    Journal of Ophthalmology, doi: 10.1155/2016/2530914, 2016.

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Department of Ophthalmology, University of Tokyo

  1. Yasuhiro Tamaki, Eizo Kawamoto, Shuichiro Eguchi, Makoto Araie and Hitoshi Fujii
    An Application of laser speckle phenomenon for non-invasive 2-dimensional evaluation of microcirculation in ocular fundus
    Jpn. J. Ophthalmol, 37, no.2, 178-186, 1993.
  2. Y. Tamaki, M. Araie, E. Kawamoto, S. Eguchi and H. Fujii
    Noncontact, Two-Dimensional Measurement of Retinal Microcirculation Using Laser Speckle Phenomenon Invest.
    Ophthalmol. Vis. Sci., 35, no.11, 3825-3834, 1994.
  3. Y. Tamaki, M. Araie, E. Kawamoto, S. Eguchi and H. Fujii
    Noncontact, Two-Dimensional Measurement of Tissue Circulation in Choroid and Optic Nerve Head Using Laser Speckle Phenomenon
    Exp. Eye Res., 60, 373-384, 1995.
  4. Y.Tamaki and M. Araie
    Time Change of Nicardipine Effect on Tissue Circulation in Retina in Living Rabbit eyes
    Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995
  5. Y. Tamaki, M. Araie, K. Tomita, M. Nagahara, A. Tomidokoro and H. Fujii
    Real-Time Measurement of Human Optic Nerve Head and Choroid Circulation, Using the Laser Speckle Phenomenon
    Jpn. J Ophthalmol., 41, 49-54, 1997.
  6. Miyuki Nagahara, Yasuhiro Tamaki, Atsuo Tomidokoro and Makoto Araie
    In Vivo Measurement of Blood Velocity in Human Major Retinal Vessels Using the Laser Speckle Method
    Invest. Ophthalmol. Vis. Sci. August 11, 2010
  7. Chihiro Mayama
    Calcium channels and their blockers in intraocular pressure and glaucoma
    European Journal of Pharmacology, Available online 1 December 2013.

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Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University

  1. Hidetaka Noma, Kanako Yasuda, Terumi Minezaki, Sho Watarai and Masahiko Shimura
    Changes of retinal flow volume after intravitreal injection of bevacizumab in branch retinal vein occlusion with macular edema: a case series
    BMC ophthalmology, 2016, 16(1), 1.

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Department of Ophthalmology, Tokyo Medical and Dental University

  1. Ryoko Soma, Muka Moriyama and Kyoko Ohno-Matsui
    Hemodynamics of focal choroidal excavations
    International Ophthalmology, 1-8, 2015.

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Tokyo Institute of Technology

  1. Tsukasa Ikemura, Akane Miyaji, Hideaki Kashima, Yuji Yamaguchi, Naoyuki Hayashi
    Ocular blood flow decreases during passive heat stress in resting humans
    Journal of Physiological Anthropology 2013, 32:23 doi:10.1186/1880-6805-32-23
  2. Tsukasa Ikemura, Naoyuki Hayashi
    Effects of Heat Stress on Ocular Blood Flow during Exhaustive Exercise
    Journal of Sports Science and Medicine (2014) 13, 172-179
  3. A. Miyaji, T. Ikemura, Y. Hamada and N. Hayashi
    Regional differences in the vascular response to CO 2 among cerebral, ocular, and mesenteric vessels.
    Artery Research, Available online 6 September 2015. doi:10.1016/j.artres.2015.08.001
  4. A. Miyaji, T. Ikemura and N. Hayashi
    Effect of Aging on the Blowout Time in Various Ocular Vessels
    Aging Sci, 2016, 4.148: 2.

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Faculty of Sport Sciences, Waseda University

  1. Tsukasa Ikemura, Hideaki Kashima, Yuji Yamaguchi, Akane Miyaji and Naoyuki Hayashi
    Inner ocular blood flow responses to an acute decrease in blood pressure in resting humans
    Physiological measurement, 36(2), 219.

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Faculty of Commerce, Yokohama College of Commerce

  1. Tsukasa Ikemura, Naoyuki Hayashi
    Inner ocular blood flow response to exercise in healthy humans
    The Journal of Physical Fitness and Sports Medicine, 6(4), 223-226, doi:10.7600/jpfsm.6.223, 2017.
  2. Tsukasa Ikemura, Katsuhiko Suzuki, Nobuhiro Nakamura, Koichi Yada and Naoyuki Hayashi
    Fluid intake restores retinal blood flow early after exhaustive exercise in healthy subjects
    European Journal of Applied Physiology, doi:10.1007/s00421-018-3839-6, 2018.

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Ophthalmology and Visual Science, Kanazawa University

  1. Yasushi Wada, Tomomi Higashide, Atsushi Nagata and Kazuhisa Sugiyama
    Longitudinal Changes in Optic Nerve Head Blood Flow in Normal Rats Evaluated by Laser Speckle Flowgraphy.
    IOVS, 57(13), 5568-5575, 2016.
  2. Yutaro Yamada, Tomomi Higashide, Sachiko Udagawa, Satoshi Takeshima, Kimikazu Sakaguchi, Koji Nitta and Kazuhisa Sugiyama
    The Relationship Between Interocular Asymmetry of Visual Field Defects and Optic Nerve Head Blood Flow in Patients with Glaucoma
    Journal of Glaucoma、doi:10.1097/IJG.0000000000001181, 2018.
  3. Yasushi Wada, Tomomi Higashide, Atsushi Nagata and Kazuhisa Sugiyama
    Effects of ripasudil, a rho kinase inhibitor, on blood flow in the optic nerve head of normal rats
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4191-6, 2018.
  4. Satoshi Takeshima, Tomomi Higashide, Masayo Kimura, Sachiko Udagawa, Yutaro Yamada, Daisuke Takemoto, Shinji Ohkubo and Kazuhisa Sugiyama
    Effects of Trabeculectomy on Waveform Changes of Laser Speckle Flowgraphy in Open Angle Glaucoma
    Investigative Ophthalmology & Visual Science, 60(2), 677-684, doi:10.1167/iovs.18-25694, 2019.

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Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University

  1. Shinichiro Fuma, Anri Nishinaka, Yuki Inoue, Kazuhiro Tsuruma, Masamitsu Shimazawa, Mineo Kondo and Hideaki Hara
    A pharmacological approach in newly established retinal vein occlusion model
    Scientific Reports, 7, doi:10.1038/srep43509, 2017.
  2. Mayu Moriguchi, Shinsuke Nakamura, Yuki Inoue, Anri Nishinaka, Maho Nakamura, Masamitsu Shimazawa and Hideaki Hara
    Irreversible Photoreceptors and RPE Cells Damage by Intravenous Sodium Iodate in Mice Is Related to Macrophage Accumulation
    Investigative Ophthalmology & Visual Science, 59(8), 3476-3487, 2018.
  3. Anri Nishinaka, Yuki Inoue, Shinichiro Fuma, Yoshifumi Hida, Shinsuke Nakamura, Masamitsu Shimazawa and Hideaki Hara
    Pathophysiological Role of VEGF on Retinal Edema and Nonperfused Areas in Mouse Eyes With Retinal Vein Occlusion
    Investigative Ophthalmology & Visual Science, 59(11), 4701-4713, 2018.

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Department of Ophthalmology, Nagoya University

  1. Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Kenta Murotani, Shigeyuki Matsui, and Hiroko Terasaki
    Diurnal Variations in Blood Flow at Optic Nerve Head and Choroid in Healthy Eyes: Diurnal Variations in Blood Flow.
    Medicine, 94(6): e819, 2015.
  2. Kosei Yanagida, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Hiroki Kaneko, Kenta Murotani, Shigeyuki Matsui and Hiroko Terasaki
    Sex-Related Differences in Ocular Blood Flow of Healthy Subjects Using Laser Speckle Flowgraphy.
    IOVS, 56(8), 4880-4890, 2015. doi:10.1167/iovs.15-16567
  3. Takeshi Iwase, Eimei Ra, Kentaro Yamamoto, Hiroki Kaneko, Yasuki Ito and Hiroko Terasaki
    Differences of Retinal Blood Flow Between Arteries and Veins Determined by Laser Speckle Flowgraphy in Healthy Subjects
    Medicine, 94(33): e1256, 2015.
  4. Takeshi Iwase, Kentaro Yamamoto, Misato Kobayashi, Eimei Ra, Kenta Murotani and Hiroko Terasaki
    What ocular and systemic variables affect choroidal circulation in healthy eyes
    Medicine, 95(43): e5102, 2016.
  5. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra and Hiroko Terasaki
    Changes in Blood Flow on Optic Nerve Head After Vitrectomy for Rhegmatogenous Retinal Detachment
    IOVS, 57(14), 6223-6233, 2016. doi:10.1167/iovs.16-20577
  6. Marie Fukami, Takeshi Iwase, Kentaro Yamamoto, Hiroki Kaneko, Shunsuke Yasuda and Hiroko Terasaki
    Changes in Retinal Microcirculation After Intravitreal Ranibizumab Injection in Eyes With Macular Edema Secondary to Branch Retinal Vein Occlusion
    IOVS, 58(2), 1246-1255, 2017. doi:10.1167/iovs.16-21115
  7. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Effects of photocoagulation on ocular blood flow in patients with severe non-proliferative diabetic retinopathy
    PLOS ONE, 12(3), e0174427, doi:10.1371/journal.pone.0174427, 2017.
  8. Marie Fukami, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Kenta Murotani and Hiroko Terasaki
    Diurnal variation of pulse waveform parameters determined by laser speckle flowgraphy on the optic nerve head in healthy subjects.
    Medicine, 96(44): e8312, 2017.
  9. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra and Hiroko Terasaki
    Change in choroidal blood flow and choroidal morphology due to segmental scleral buckling in eyes with rhegmatogenous retinal detachment
    Scientific Reports, 7(1), 5997, doi:10.1038/s41598-017-05126-1, 2017.
  10. Takeshi Iwase, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra, Yasuki Ito, Kenta Murotani and Hiroko Terasaki
    Investigation of causes of sex-related differences in ocular blood flow in healthy eyes determined by laser speckle flowgraphy
    Scientific Reports, 7(1), 13878, doi:10.1038/s41598-017-14118-0, 2017.
  11. Yuji Mikoshiba, Takeshi Iwase, Yoshitaka Ueno, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulation
    Scientific Reports, 8(1), 14128, doi:10.1038/s41598-018-32487-y, 2018.
  12. Takeshi Iwase, Tomohiko Akahori, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Evaluation of optic nerve head blood flow in response to increase of intraocular pressure
    Scientific Reports, 8(1), 17235, doi:10.1038/s41598-018-35683-y, 2018.

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Department of Ophthalmology, Osaka Medical College

  1. S.Kojima, T. Sugiyama, M. Toda, H. Oku, K. Shimizu, O. Ishida, M. Nakajima and I. Azuma
    Effect of nitric oxide on rabbit optic nerve head circulation
    Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
  2. Okuno T, Sugiyama T, Ikeda T
    Correlation between Heidelberg Retina Flowmeter HRF and laser speckle flowgrafy LSFG
    Invest Ophthalmol Vis Sci 2001;42:S84.
  3. Okuno T, Sugiyama T, Kohyama M, Kojima S, Oku H, Ikeda T
    Ocularblood flow changes after dynamic exercise in humans
    Eye. 2006 Jul;20(7):796-800. Epub 2005 Jul 8.
  4. Sugiyama T, Oku H, Komori A, et al
    Effect of P2X7 receptor activation on the retinal blood velocity of diabetic rabbits
    Arch Ophthalmol 124:1143-1149,2006
  5. Sugiyama T, Kojima S, Ishida O, Ikeda T
    Changes in optic nerve head blood flow induced by the combined therapy of latanoprost and beta blockers.
    Acta Ophthalmol 2008 Dec 2.
  6. Sugiyama T, Mashima Y, Yoshioka Y, Oku H, Ikeda T
    Effect of unoprostone on topographic and blood flow changes in the ischemic optic nerve head of rabbits.
    Arch Ophthalmol 127(4):454-9,2009
  7. Sugiyama T, Araie M, Riva CE, Schmetterer L, Orgul S
    Use of laser speckle flowgraphy in ocular blood flow research.
    Acta Ophthalmol. :2009 Sep 2.
  8. Tetsuya Sugiyama, Maho Shibata, Sumiko Kajiura, Takashi Okuno, Masahiro Tonari, Hidehiro Oku and Tsunehiko Ikeda
    Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits.
    Investigative ophthalmology & visual science, 52(1): 64-69, 2011.
  9. Shibata M, Oku H, Sugiyama T, Kobayashi T, Tsujimoto M, Okuno T, Ikeda T.
    Disruption of Gap Junctions May Be Involved in Impairment of Autoregulation in Optic Nerve Head Blood Flow of Diabetic Rabbits
    IOVS 2011; 52: 2152-2159.
  10. Maho Shibata, Tetsuya Sugiyama, Masaaki Hoshiga, Junko Hotchi, Takashi Okuno, Hidehiro Oku, Toshiaki Hanafusa and Tsunehiko Ikeda
    Changes in optic nerve head blood flow, visual function, and retinal histology in hypercholesterolemic rabbits
    Experimental Eye Research, 93(6), 818-824, 2011.
  11. Maho Shibata, Tetsuya Sugiyama, Takuji Kurimoto,Hidehiro Oku, Takashi Okuno, Takatoshi Kobayashi ,Tsunehiko Ikeda
    Involvement of Glial Cells in the Autoregulation of Optic Nerve Head Blood Flow in Rabbits
    IOVS 2012; 53: doi: 10.1167/iovs.11-9316
  12. Teruyo Kida, Josef Flammer, Hidehiro Oku, Katarzyna Konieczka, Seita Morishita, Taeko Horie and Tsunehiko Ikeda
    Vasoactivity of retinal veins: A potential involvement of endothelin-1 (ET-1) in the pathogenesis of retinal vein occlusion (RVO).
    Experimental Eye Research, doi:10.1016/j.exer.2018.07.016, 2018.
  13. Teruyo Kida, Josef Flammer, Hidehiro Oku, Katarzyna Konieczka, Seita Morishita, Taeko Horie and Tsunehiko Ikeda
    Vasoactivity of retinal veins
    Data in Brief, doi:10.1016/j.dib.2018.09.070, 2018.
  14. Mari Ueki, Tetsuya Sugiyama, Ryohsuke Kohmoto, Shota Kojima, Michiko Maeda, Emika Nemoto, Satoru Tokuoka and Tsunehiko Ikeda
    Blood Flow in the Optic Nerve Head Changes after Disc Hemorrhage in Primary Open Angle Glaucoma
    EC Ophthalmology, 10(3), 230-235, 2019.

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Nakano Eye Clinic

  1. Tetsuya Sugiyama
    Basic Technology and Clinical Applications of the Updated Model of Laser Speckle Flowgraphy to Ocular Diseases
    Photonics, 1, no.3, 220-234, 2014. doi:10.3390/photonics1030220
  2. Tetsuya Sugiyama, Hajime Nakamura, Emiko Shimizu, Kazuaki Miyamoto and Ryozo Yamada
    Clinical Usefulness of the Measurement of Optic Nerve Head Blood Flow in Myopic Normal-Tension Glaucoma
    International Journal of Ophthalmic Research 2015 June 1(1): 11-18
  3. Tetsuya Sugiyama
    Coexisting Normal-Tension Glaucoma and Deficiencies of Folic Acid and Vitamin B6 (Pyridoxal)
    International Journal of Ophthalmology and Clinical Research, 2(4):037, 2015.
  4. Tetsuya Sugiyama and Hajime Nakamura
    Increased Short-Term Fluctuation in Optic Nerve Head Blood Flow in a Case of Normal-Tension Glaucoma by the Use of Laser Speckle Flowgraphy.
    Vision 2016, 1, 5.
  5. Tetsuya Sugiyama, Emiko Shimizu and Kazuaki Miyamoto
    Ocular Blood Flow Changes in a Case with Nonarteritic Ischemic Optic Neuropathy Complicated by Obstructive Sleep Apnea Syndrome
    EC Ophthalmology, 9.6, 361-367, 2018.

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Tane Memorial Eye Hospital

  1. T.Maeno, R.Tano, M.Sakamoto, N.Onishi, K.Kakurai, T.Yamada, H.Fujii, T.Mano
    Measurement of Retinal Blood Flow Volume by Laser Speckle Flowgraphy Before and After Arteriovenous Sheathotomy for Branch Retinal Vein Occlusion
    ARVO, 2008, (4265/A358)
  2. R.Tano, M.Sakamoto, M.Ikeda, S.Sugita, H.Fujii, T.Mano, T.Maeno
    Analysis of Retinal Blood Flow by Laser Speckle Flowgraphy in a Case With Central Retinal Vein Occlusion After Radial Optic Neurotomy
    ARVO, 2008, (4274/A367)

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Department of Ophthalmology, Kyoto University

  1. Yoshimasa Kuroda, Akihito Uji and Nagahisa Yoshimura
    Factors associated with optic nerve head blood flow and color tone: a retrospective observational study.
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1-8, 2016.

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Department of Ophthalmology, Saneikai Tsukazaki Hospital

  1. Daisuke Nagasato, Yoshinori Mitamura, Kentaro Semba, Kei Akaiwa, Toshihiko Nagasawa, Yuki Yoshizumi, Hitoshi Tabuchi and Yoshiaki Kiuchi
    Correlation between optic nerve head circulation and visual function before and after anti-VEGF therapy for central retinal vein occlusion: prospective, interventional case series
    BMC ophthalmology, 16(1), doi:10.1186/s12886-016-0211-7, 2016.

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Department of Ophthalmology, Nara Medical University

  1. Okamoto M, Matsuura T, Ogata N
    Ocular blood flow before, during, and after vitrectomy determined by laser speckle flowgraphy.
    Ophthalmic Surg Lasers Imaging Retina. 2014 Mar 1;45(2):118-24. doi: 10.3928/23258160-20140306-04.
  2. Masahiro Okamoto, Toyoaki Matsuura and Nahoko Ogata
    EFFECTS OF PANRETINAL PHOTOCOAGULATION ON CHOROIDAL THICKNESS AND CHOROIDAL BLOOD FLOW IN PATIENTS WITH SEVERE NONPROLIFERATIVE DIABETIC RETINOPATHY.
    RETINA, 36(4), 805-811, 2016.
  3. Masahiro Okamoto, Mariko Yamashita and Nahoko Ogata
    Effects of intravitreal injection of ranibizumab on choroidal structure and blood flow in eyes with diabetic macular edema
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1-8, doi: 10.1007/s00417-018-3939-3, 2018.

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Department of Anesthesiology, Nara Medical University

  1. Hironobu Hayashi, Masahiro Okamoto, Hideaki Kawanishi, Toyoaki Matsuura, Nobuoki Tabayashi, Shigeki Taniguchi and Masahiko Kawaguchi
    Ocular blood flow measured by laser speckle flowgraphy during aortic arch surgery with antegrade selective cerebral perfusion.
    Journal of Cardiothoracic and Vascular Anesthesia, 2016.
  2. Hironobu Hayashi, Masahiro Okamoto, Hideaki Kawanishi, Nobuoki Tabayashi, Toyoaki Matsuura, Shigeki Taniguchi and Masahiko Kawaguchi
    Association between optic nerve head blood flow measured by laser speckle flowgraphy and radial arterial pressure during aortic arch surgery.
    Journal of Cardiothoracic and Vascular Anesthesia, 2017.

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Department of Ophthalmology, Tokushima University

  1. Takamasa Kinoshita , Junya Mori, Natsuki Okuda, Hiroko Imaizumi, Masanori Iwasaki, Miho Shimizu, Hirotomo Miyamoto, Kei Akaiwa, Kentaro Semba, Shozo Sonoda, Taiji Sakamoto and Yoshinori Mitamura
    Effects of Exercise on the Structure and Circulation of Choroid in Normal Eyes.
    PLOS ONE, 11(12), e0168336, 2016.

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Department of Ophthalmology, Kyushu University

  1. Hiroshi Enaida, Kenji Okamoto, Hitoshi Fujii and Tatsuro Ishibashi
    LSFG Findings of Proliferative Diabetic Retinopathy After Intravitreal Injection of Bevacizumab
    Ophthalmic Surgery, Lasers and Imaging 41 Online(): e1-e3, 2010.
  2. Masato Akiyama, Yasuhiro Ikeda, Noriko Yoshida, Shoji Notomi, Yusuke Murakami, Toshio Hisatomi, Hiroshi Enaida, Tatsuro Ishibashi
    Therapeutic efficacy of topical unoprostone isopropyl in retinitis pigmentosa
    Acta Ophthalmologica, DOI: 10.1111/aos.12293, 2013.
  3. Yusuke Murakami, Yasuhiro Ikeda, Masato Akiyama, Kota Fujiwara, Noriko Yoshida, Shunji Nakatake, Shoji Notomi, Takahiro Nabeshima, Toshio Hisatomi, Hiroshi Enaida and Tatsuro Ishibashi
    Correlation between macular blood flow and central visual sensitivity in retinitis pigmentosa.
    Acta Ophthalmologica, DOI: 10.1111/aos.12693, 2015.
  4. Yusuke Murakami, Jun Funatsu, Shunji Nakatake, Kohta Fujiwara, Takashi Tachibana, Yoshito Koyanagi, Toshio Hisatomi, Shigeo Yoshida, Shozo Sonoda, Taiji Sakamoto, Koh-Hei Sonoda and Yasuhiro Ikeda
    Relations Among Foveal Blood Flow, Retinal-Choroidal Structure, and Visual Function in Retinitis Pigmentosa
    Investigative Ophthalmology & Visual Science, 59(2), 1134-1143, 2018.

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Institute of Health Science, Kyushu University

  1. Hayashi N, Ikemura T, Someya N
    Effects of dynamic exercise and its intensity on ocular blood flow in humans.
    Eur J Appl Physiol. 2011
  2. Ikemura T, Someya N, Hayashi N
    Autoregulation in the ocular and cerebral arteries during the cold pressor test and handgrip exercise.
    Eur J Appl Physiol.  2011
  3. Hideaki Kashima, Naoyuki Hayashi
    Basic Taste Stimuli Elicit Unique Responses in Facial Skin Blood Flow
    PLOS ONE 6(12) 2011: e28236. doi:10.1371/journal.pone.0028236
  4. Naoyuki Hayashi, Tsukasa Ikemura, Nami Someya
    Changes in ocular flow induced by hypo- and hypercapnia relate to static visual acuity in humans
    Eye Reports 2011, volume.1:e8, Page.20-24
  5. Tsukasa Ikemura, Naoyuki Hayashi
    Ocular circulatory responses to exhaustive exercise in humans
    Eur J Appl Physiol. 2012

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Department of Ophthalmology, University of Occupational and Environmental Health

  1. K.Nagaya, H. Takahashi, H. Fujii
    Optic nerve head microcirculation using laser speckle flowgraphy in patients with normal tension glaucoma
    ARVO, 1999, #1457/B365

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Yamana Eye Hospital

  1. Y.Yamana, M. Matsuo, N. Konishi and H. Fujii
    Heidelberg Retina Flowmeter and Laser Speckle Flowgraphy System: a comparative evaluation
    Microcirculation Annual, 13, 195-196, 1997.
  2. Y.Yamana, M. Matsuo, N. Konishi and H. Fujii
    Peripapillary tissue, retinal vessels and optic nerve head blood flow rates using laser speckle flowgraphy
    20th European Conference on Microcirculation, 219-223, 1998.
  3. Y.Yamana, M. Matsuo, K. Goya, N. Konishi and H. Fujii
    Retinal Vessels and Peripapillary Tissue Blood Flow in Diabetes Using Laser Speckle Flowgraphy System: a comparative evaluation
    Microcirculation Annual, 15,117-118, 1999.
  4. Y.Yamana, M. Matsuo, Y. Koketu, K. Goya, M. Wakisaka, M. Iwase, M.Yoshinari, N. Konishi, H. Fujii
    Effect Acute Hyperglycemia on Chorio-Retinal Blood Flow in IGT and Diabetes Mellitus
    Microcirculation Annual, 18, 85-86, 2002
  5. Y.Yamana, M. Matsuo, Y. Koketsu, K. Goya, M. Yoshinari, N. Konishi, H.Fujii
    Dysregulation of the Postprandial Retinal Blood Flpw in Type 2 Diabetes
    European Society for Microcirculation, 18,95-98, 2002

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Department of Ophthalmology, Saga University

  1. Hiroshi Enaida, Shinji Nagata, Atsunobu Takeda, Shintaro Nakao, Yasuhiro Ikeda and Tatsuro Ishibashi
    Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy
    Japanese Journal of Ophthalmology, 1-7, doi:10.1007/s10384-016-0472-y, 2016.

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Department of Ophthalmology, Nagasaki University

  1. Matsumoto Makiko, Suzuma Kiyoshi, Fukazawa Yoshiko, Yamada Yoshihisa, Tsuiki Eiko, Fujikawa Azusa and Kitaoka Takashi
    Retinal blood flow levels measured by Laser Speckle Flowgraphy in patients who received intravitreal bevacizumab injection for macular edema secondary to central retinal vein occlusion.
    Retinal Cases and Brief Reports, 8(1), 60-66, 2014.
  2. Y.Yamada, K.Suzuma, M.Matsumoto, E.Tsuiki, A.Fujikawa, T.Harada and T.Kitaoka
    Retinal Blood Flow Correlates to Aqueous Vascular Endothelial Growth Factor in Central Retinal Vein Occlusion.
    RETINA, 35(10), 2037-2042, 2015.
  3. Makiko Matsumoto, Kiyoshi Suzuma, Yoshihisa Yamada, Eiko Tsuiki, Azusa Fujikawa and Takashi Kitaoka
    Retinal blood flow after intravitreal bevacizumab is a predictive factor for outcomes of macular edema associated with central retinal vein occlusion.
    Retina, doi:10.1097/IAE.0000000000001531, 2017.

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Department of Ophthalmology, University of Miyazaki

  1. Tomoyuki Maekubo, Hideki Chuman, Nobuhisa Nao-i
    Laser speckle flowgraphy for differentiating between nonarteritic ischemic optic neuropathy and anterior optic neuritis
    Jpn. J. Ophthalmol., May 2013, (doi:10.1007/s10384-013-0246-8)
  2. Takako Hidaka, Hideki Chuman and Nobuhisa Nao-I
    Evaluation of optic nerve head blood flow in normal rats and a rodent model of non-arteritic ischemic optic neuropathy using laser speckle flowgraphy
    Graefe's Archive for Clinical and Experimental Ophthalmology, 255(10), 1973-1980, 2017.
  3. Hideki Chuman, Takako Sugimoto and Nobuhisa Nao-I
    Vasodilatory effect of L-arginine on isolated rabbit and human posterior ciliary arteries in vitro and increased optic disc blood flow in vivo.
    Graefe's Archive for Clinical and Experimental Ophthalmology, 255(12), 2381-2388, 2017.

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Devers Eye Institute, Legacy Health System

  1. Y.Liang, L. Wang, G. Cull, H. Fujii, J.C. Downs.
    Systemic Blood Pressure Determines the Magnitude of IOP-Induced Blood Flow Change in the Optic Nerve Head of Non-Human Primate
    ARVO, 2008, (3265)
  2. Yi Liang, J. Crawford Downs, Brad Fortune, Grant Cull, George A. Cioffi, Lin Wang
    Impact of Systemic Blood Pressure on the Relationship between Intraocular Pressure and Blood Flow in the Optic Nerve Head of Nonhuman Primates
    IOVS, 50:2154-2160, May 2009
  3. Yi Liang, Brad Fortune, Grant Cull, George A. Cioffi, Lin Wang
    Quantification of dynamic blood flow autoregulation in Optic nerve head of rhesus monkeys
    Experimental Eye Research, 90, no.2: 203-209, 2010.
  4. Lin Wang, Grant A. Cull, Chelsea Piper, Claude F. Burgoyne, Brad Fortune
    Anterior and Posterior Optic Nerve Head Blood Flow in Nonhuman Primate Experimental Glaucoma Model Measured by Laser Speckle Imaging Technique and Microsphere Method
    IOVS, November 20, 2012 IOVS-12-10911
  5. Chelsea Piper, Brad Fortune, Grant Cull, George A. Cioffi and Lin Wang
    BASAL BLOOD FLOW AND AUTOREGULATION CHANGES IN THE OPTIC NERVE OF RHESUS MONKEYS WITH IDIOPATHIC BILATERAL OPTIC ATROPHY
    IOVS, January 3, 2013 IOVS-12-9773
  6. Grant Cull, Claude F. Burgoyne, Brad Fortune and Lin Wang
    Longitudinal Hemodynamic Changes within the Optic Nerve Head in Experimental Glaucoma
    IOVS, June 4, 2013 IOVS-13-12013
  7. Lin Wang, Claude F. Burgoyne, Grant Cull, Simmon Thompson and Brad Fortune
    Static Blood flow Autoregulation in the Optic Nerve Head in Normal and Experimental Glaucoma
    IOVS, January 16, 2014 IOVS-13-13716
  8. Jintao Yu, Yi Liang, Simon Thompson, Grant Cull, Lin Wang
    Parametric transfer function analysis and modeling of blood flow autoregulation in the optic nerve head
    Int J Physiol Pathophysiol Pharmacol 2014;6(1):13-22
  9. Lin Wang, Grant Cull, Claude F. Burgoyne, Simon Thompson and Brad Fortune
    Longitudinal Alterations in the Dynamic Autoregulation of Optic Nerve Head Blood Flow Revealed in Experimental Glaucoma
    IOVS, May 8, 2014 IOVS-14-14020. doi:10.1167/iovs.14-14020
  10. Lin Wang, Grant A. Cull and Brad Fortune
    Optic Nerve Head Blood Flow Response to Reduced Ocular Perfusion Pressure by Alteration of Either the Blood Pressure or Intraocular Pressure
    Current Eye Research, Posted online on June 9, 2014. (doi:10.3109/02713683.2014.924146)
  11. Grant Cull, Reinhard Told, Claude F. Burgoyne, Simon Thompson, Brad Fortune and Lin Wang
    Compromised Optic Nerve Blood Flow and Autoregulation Secondary to Neural DegenerationHemodynamics Secondary to Optic Nerve Degeneration.
    IOVS, 56(12), 7286-7292, 2015.

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Department of Veterinary Medicine & Surgery, University of Missouri

  1. Shyam S. Chaurasia, Rayne R. Lim, Bhav H. Parikh, Yeo Sia Wey, Bo Bo Tun, Tien Yin Wong, Chi D. Luu, Rupesh Agrawal, Arkasubhra Ghosh, Alessandra Mortellaro, Elizabeth Rackoczy, Rajiv R. Mohan and Veluchamy A. Barathi
    The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
    Scientific reports, 8(1), 2847, doi:10.1038/s41598-018-21198-z, 2018.

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Department of Clinical Pharmacology, Medical University of Vienna

  1. P.A. Wozniak, N. Luft, G. Aschinger, K. Fondi, A.M. Bata, K.J. Witkowska, D. Schmidl, R.M. Werkmeister, M. Bolz, G. Garhöfer and L. Schmetterer
    The assessment of ocular blood flow with laser speckle flowgraphy in healthy caucasian.
    Acta Ophthalmologica, 2016, 94.S256. doi: 10.1111/j.1755-3768.2016.0391
  2. Nikolaus Luft, Piotr A. Wozniak, Gerold C. Aschinger, Klemens Fondi, Ahmed M. Bata, René M. Werkmeister, Doreen Schmidl, Katarzyna J. Witkowska, Matthias Bolz, Gerhard Garhöfer and Leopold Schmetterer
    Measurements of Retinal Perfusion Using Laser Speckle Flowgraphy and Doppler Optical Coherence Tomography
    IOVS, 57(13), 5417-5425, 2016.
  3. Nikolaus Luft, Piotr A. Wozniak, Gerold C. Aschinger, Klemens Fondi, Ahmed M. Bata, René M. Werkmeister, Doreen Schmidl, Katarzyna J. Witkowska, Matthias Bolz, Gerhard Garhöfer and Leopold Schmetterer
    Ocular Blood Flow Measurements in Healthy White Subjects Using Laser Speckle Flowgraphy
    PLOS ONE, 11(12), e0168190, 2016.
  4. D.Schmidl, K.Witkowska, N.Luft, M.Bolz, K.Fondi, A.Bata, P.Wozniak, R.Werkmeister, G.Garhofer and L.Schmetterer
    Assessment of retinal blood flow using Laser Speckle Flowgraphy
    Acta Ophthalmologica, 95.S259, doi: 10.1111/j.1755-3768.2017.01145, 2017.
  5. Katarzyna J. Witkowska, Ahmed M. Bata, Giacomo Calzetti, Nikolaus Luft, Klemens Fondi, Piotr A. Wozniak, Doreen Schmidl, Matthias Bolz, Alina Popa-Cherecheanu, René M. Werkmeister, Gerhard Garhöfer and Leopold Schmetterer
    Optic nerve head and retinal blood flow regulation during isometric exercise as assessed with laser speckle flowgraphy
    PLOS ONE, 12(9), e0184772, doi: 10.1371/journal.pone.0184772, 2017.
  6. Giacomo Calzetti, Klemens Fondi, Ahmed M Bata, Nikolaus Luft, Piotr A Wozniak, Katarzyna J Witkowska, Matthias Bolz, Alina Popa-Cherecheanu, René M Werkmeister, Doreen Schmidl, Gerhard Garhöfer and Leopold Schmetterer
    Assessment of choroidal blood flow using laser speckle flowgraphy
    British Journal of Ophthalmology, bjophthalmol-2017-311750, doi: 10.1136/bjophthalmol-2017-311750, 2018.
  7. Fondi K, Bata AM, Luft N, Witkowska KJ, Werkmeister RM, Schmidl D, Bolz M, Schmetterer L and Garhöfer G
    Evaluation of flicker induced hyperemia in the retina and optic nerve head measured by Laser Speckle Flowgraphy.
    PLOS ONE, 13(11), e0207525, doi:10.1371/journal.pone.0207525, 2018.

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Department for Ophthalmology, Kepler University Hospital

  1. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
    Laser speckle flowgraphy derived characteristics of optic nerve head perfusion in normal tension glaucoma and healthy individuals: a Pilot study.
    Scientific Reports, 8(1), 5343, doi:10.1038/s41598-018-23149-0, 2018.
  2. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
    Short-term effect on the ocular circulation inducedby unilateral intravitreal injection of aflibercept inage-related maculopathy
    Acta Ophthalmologica, doi:10.1111/aos.14098, 2019.
  3. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
    Differences in Optic Nerve Head Blood Flow Regulation in Normal Tension Glaucoma Patients and Healthy Controls as Assessed with Laser Speckle Flowgraphy During the Water Drinking Test
    Journal of Glaucoma, doi:10.1097/IJG.0000000000001258, 2019.

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Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital

  1. X. Wei, A. Barathi, B.B. Sai, P.K. Balne, N. Khandelwal and R. Agrawal
    Assessment of chorioretinal blood flow and vessel diameter by laser speckle flowgraphy in three animal models
    Acta Ophthalmologica, 2016, 94.S256. doi: 10.1111/j.1755-3768.2016.0566

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Universiti Teknologi PETRONAS

  1. M. S. Bhatti, W. Rasheed, T. B. Tang and A. Laude
    Investigating eye-strain due to prolonged exposure to low resolution multimedia using LSFG
    2016 6th International Conference on Intelligent and Advanced Systems (ICIAS), doi:10.1109/ICIAS.2016.7824096, 2016.
  2. Mehwish Saba Bhatti, Tong Boon Tang and Augustinus Laude
    Effects of water drinking test on ocular blood flow waveform parameters: A laser speckle flowgraphy study
    PLoS ONE 12(7): e0181512. doi:10.1371/journal.pone.0181512, 2017.
  3. Mehwish Saba Bhatti, Tong Boon Tang and Hui Cheng Chen
    Ocular Blood Flow in Rabbits under Deep Anesthesia: A Real-Time Measurement Technique and Its Application in Characterizing Retinal Ischemia
    Scientific Reports, 8(1), 5713, doi:10.1038/s41598-018-24141-4, 2018.
  4. Aishah Ismail, Mehwish S. Bhatti, Ibrahima Faye, Cheng Kai Lu, Augustinus Laude and Tong Boon Tang
    Pulse waveform analysis on temporal changes in ocular blood flow due to caffeine intake: a comparative study between habitual and non-habitual groups
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-018-4030-9, 2018.
  5. Aishah Ismail, Tong Boon Tang, Faye Ibrahima and Chen Hui Cheng
    Animal Model - Investigation of Laser Speckle Flowgraphy for Early Carotid Artery Stenosis Detection
    2018 International Conference on Intelligent and Advanced System (ICIAS), doi:10.1109/ICIAS.2018.8540566, 2018.

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Senju Pharmaceutical Co.,Ltd

  1. Hiroaki Takahashi, Tetsuya Sugiyama, Hideki Tokushige, Takatoshi Maeno, Toru Nakazawa, Tsunehiko Ikeda, Makoto Araie
    Comparison of CCD-equipped laser speckle flowgraphy with hydrogen gas clearance method in the measurement of optic nerve head microcirculation in rabbits
    Experimental Eye Research(2012), http://dx.doi.org/10.1016/j.exer.2012.12.003

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Department of Computer Science and Electronics, Kyushu Institute of Technology

  1. H.Fujii
    Visualization of retinal blood flow by laser speckle flowgraphy
    Med. Bio. Eng. & Comp., 32, no.3, 302-304, 1994.
  2. Naoki Konishi, Hitoshi Fujii
    Real-time Visualization of retinal microcirculation by laser flowgraphy
    Optical Enginnering, 34, no.3,753-757, 1995.
  3. H. Fujii, N. Konishi, K. Okamoto and Y. Tsuchihashi
    Evaluation of Retinal Microcirculation by Real-Time Laser Flowgraphy
    Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
  4. Hitoshi Fujii and Naoki Konishi
    Visualization of Blood Flow Using Laser Speckle Method
    Proceedings of 18th Annual International Conference, No.688 1996.
  5. Hitoshi Fujii Yoshihiko Tsuchihashi and Naoki Konishi
    Evaluation of Retinal Microcirculation by Real-Time Laser Flowgraphy(II)
    Proc. 3rd Internet World Congress on Biomedical Sciences, 1996
  6. Hitoshi Fujii
    Laser Speckle Blood Flowgraphy Medical Diagnostic Techniques and Procedures, Megha Singh et.al. Ed.,
    216-224 (Narosa Publishing House, New Delhi, London, 1999)
  7. Naoki Konishi, Yoshinori Tokimoto, Kazuhiro Kohra and Hitoshi Fujii
    New Laser Speckle Flowgraphy System Using CCD Camera
    Optical Review, 9, No.4, 163-169, 2002
  8. Min-Chul Lee, Naoki Konishi and Hitoshi Fujii
    Blood Flow Analyses of Skin Tissue Under the Sacrum Using Laser Speckle Flowgraphy
    Optical Review, 10, No. 6, 562-566, 2003

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