Understanding Neurovascular Coupling
Our cutting-edge flicker-illuminated fundus camera system enables exploration of neurovascular coupling. This innovative tool is designed to enhance understanding of the intricate connections between the cardiovascular and nervous systems through detailed ocular blood flow responses. Join us in advancing ocular research and uncovering the mysteries of neurovascular interactions.
Can blood flow responces indicate ultra-early therapeutic intervention potential?
The fundus is the only place
in the body where blood vessels
can be observed directly.
Measuring not just blood flow volume, but its waveform — the quality of flow — to capture the earliest signals of vascular change. That is what LSFG makes possible.
Softcare is the company that first commercialized LSFG technology as a certified medical device, and continues to advance it.
Blood flow is the foundation of life.
Every cell in the human body depends on blood flow to receive oxygen and nutrients, and to remove metabolic waste. From the heart to the brain, to the eye, to the fingertips — blood flow sustains every organ, every moment.
When blood flow falters,
the body suffers.
Impaired blood flow underlies many of the most serious diseases known to medicine. What these conditions share is a common origin: disruption of blood flow at the microvascular level.
Critically, changes in blood flow often precede structural damage. Observing blood flow continuously offers a window into the earliest stages of disease — before irreversible harm has occurred.
Flow volume tells you something.
Flow waveform tells you more.
The dynamic pattern of each cardiac cycle — systolic peaks, diastolic troughs, pulsatility indices — carries far richer data about the true condition of the microvasculature than volume alone.
And where is the ideal site to observe this waveform?
The Fundus (Retina and Choroid).
The fundus is the only tissue in the human body where blood vessels can be observed directly, low-invasively, and in real time. Fundus microcirculation reflects the systemic microvascular environment — making the fundus a uniquely privileged window into the body's vascular health.
From research
to clinical practice.
Softcare is the company that first commercialized LSFG technology as a certified medical device, and continues to advance it.
publications
worldwide
in Japan
510(k)
From the fundus,
a window into systemic vascular health.
LSFG technology has been utilized in a broad and growing range of research fields, reflecting the fundus's unique position as a direct and low-invasive observation point for microvascular physiology.
Blood flow assessment holds the potential to inspire entirely new research themes — from the elucidation of disease mechanisms to a deeper understanding of human health. We look forward to the discoveries that lie ahead, together with researchers worldwide.
Blood vessels are working quietly, right now.
Our mission: to bring the technology that listens
to their voice — to the world.
Softcare Co., Ltd.










